Precision Vancomycin Dosing. Transparent. Affordable. Guideline-Compliant.
Vancomyzer™ is the first AUC-guided dosing platform that shows you every calculation — built on the Colin 2019 model, priced for every hospital.
70% of U.S. Hospitals Lack AUC Dosing Software
The 2020 ASHP/IDSA guidelines mandate AUC-based vancomycin monitoring. Most hospitals can't afford to comply.
Expensive
Enterprise platforms (InsightRX, DoseMeRx) don’t publish prices, but cost-benefit literature simulates ranges up to $50K+ per year. Most community hospitals can’t afford the upper end.
Opaque
Competitors use black-box algorithms. Pharmacists can’t verify the math.
Inaccessible
70% of surveyed U.S. hospitals had not implemented AUC dosing as of 2022 (Brixner et al., AJHP). Of 5,121 community hospitals, most still rely on trough-based monitoring.
Source: 2020 ASHP/ACCP/IDSA/SIDP Consensus Guidelines (Rybak et al.)
Vancomyzer™ — Show Your Math
The only vancomycin dosing platform where every PK parameter, equation, and assumption is visible and verifiable.
Patient Parameters
PK Parameters (Colin 2019)
Concentration-Time Profile
Target: 400–600 mg·h/L • Within therapeutic range
Full Bayesian MAP Estimation
Nelder-Mead optimization for maximum a posteriori parameter estimation.
Colin 2019 2-Compartment Model
Peer-reviewed population PK model for general adult vancomycin dosing.
Obesity-Specific FFM-Based Dosing
Automatic FFM model for BMI ≥ 40 — Smit 2020 + Zhang 2024. No other free calculator does this.
AUC₂₄ Target: 400–600 mg·h/L
Per 2020 ASHP/IDSA/PIDS consensus guidelines.
No Cockcroft-Gault — Direct SCr
Direct serum creatinine covariate for more accurate renal estimation.
RRT Safety Block
Automatic block for renal replacement therapy patients — model not validated.
DOI-Linked References on Every Result
Every calculation links back to published literature you can verify.
How Vancomyzer™ Compares
A transparent look at the vancomycin dosing landscape.
| Feature | Vancomyzer™ | PrecisePK | InsightRX | DoseMeRx | VancoCalc |
|---|---|---|---|---|---|
| Annual Cost (Community Hospital) | $0–$9,500 | $5K–$15K+ | $20K–$150K | $15K–$80K | Free |
| Transparent Math | Full | Semi | Black Box | Black Box | Partial |
| Bayesian PK Model | Colin 2019 | Literature Library | Proprietary | Proprietary | None |
| AUC-Guided (2020 Guidelines) | Basic | ||||
| Free Tier | Trial only | ||||
| No EMR Integration Required | |||||
| Literature References Built-In | Inline DOIs | Links only | Limited | Limited | |
| Obesity-Specific FFM Model (BMI ≥ 40) | Automatic | Unconfirmed | Proprietary | ||
| Equations Displayed with DOI Citations | Every equation | Parameters only | Black box | Black box | Varies |
PrecisePK pricing estimated from industry benchmarks; not publicly disclosed. InsightRX and DoseMeRx pricing from published sources and industry reports. All feature data sourced from vendor websites and published literature as of 2026.
The Market Opportunity
Global TAM in clinical PK dosing software
U.S. hospitals (AHA Fast Facts, 2026)
Have NOT adopted any AUC dosing tool
U.S. adult obesity prevalence (CDC NHANES, 2024). Over 100M adults need weight-aware dosing.
Obesity in Hidalgo County, TX — above the national average. Vancomyzer™ was built for this population.
The 2020 ASHP/IDSA guidelines mandate AUC-based vancomycin monitoring. Most enterprise platforms keep their math hidden and their pricing private. We built a transparent alternative designed for community hospital budgets.
Globally, 16% of adults — over 890 million people — live with obesity (WHO, 2022). Standard vancomycin PK models were not built for this population. Vancomyzer™ was.
Vancomyzer™ Is Just the Beginning
Dōsys is building the transparent pharmacokinetic intelligence layer for hospital pharmacy systems worldwide.
Vancomyzer™
Vancomycin AUC Dosing
Dōsys Amino™
Aminoglycosides
Dōsys TPN™
Total Parenteral Nutrition
Dōsys Renal™
Renal Dose Adjustment
Dōsys Enterprise API
EMR Integration Platform
Built by a Clinical Pharmacist,
for Clinical Pharmacists
“I built Vancomyzer because I got tired of trusting black-box algorithms with my patients' safety. Every pharmacist deserves to see the math behind a dosing recommendation — and every hospital deserves access to guideline-compliant tools, regardless of budget.”
Mario Cardenas, PharmD, MBA
Founder & CEO, Dosys Health LLC
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