Clinical pharmacy thought leadership, vancomycin dosing insights, and updates from the Dōsys team.
Vancomycin is hydrophilic. It does not distribute into fat. Yet every major dosing model uses total body weight for volume of distribution — even in patients with Class III Obesity (BMI ≥ 40). Here's why that matters clinically, and what Vancomyzer™ does about it.
A comprehensive guide to AUC-based vancomycin monitoring, why troughs are obsolete, how Bayesian estimation works, and how community hospitals can implement guideline-compliant dosing.
Clinical evidence that AUC-guided vancomycin monitoring significantly reduces nephrotoxicity compared to trough-based approaches. Cost data, risk factors, and practical prevention strategies.
A practical buyer's guide for pharmacy directors evaluating AUC-guided vancomycin dosing software. Comparison framework covering transparency, cost, model validation, and implementation.
Evidence-based updates for pharmacy professionals. No spam.